Searchable abstracts of presentations at key conferences in endocrinology

ea0062p28 | Poster Presentations | EU2019

Alemtuzumab induced thyrotoxicosis in a patient undergoing autologous haematopoietic stem cell transplant for multiple sclerosis

Esdaile Harriet , Hinton Richard , Sheridan Helena , Rogosic Srdan , Pavlu Jiri , Olavarria Eduardo , Gabriel Ian

Case History: A 37 year old female underwent an elective autologous stem cell transplant (ASCT) for multiple sclerosis (MS), with cyclophosphamide and anti-thymocyte (ATG) conditioning. She had previously received two doses of alemtuzumab, with the last dose 12 months prior to ASCT. Baseline thyroid function was normal pre atemluzumab. 3 months prior to dose 2 (18 months post first dose), subclinical hyperthryoidism was present with a raised TSH antibody (0.08 unit/ml). There ...